Michał Bartoszewicz — creator of the Polycentric Aging Framework
I developed the Polycentric Aging Framework (PAF) to organise mechanisms of aging and constraints on potential rejuvenation. On this website I discuss aging biology and scientific publications, distinguishing research findings from interpretations and questions requiring further tests.
Model authorship and publication authorship
I originated the Polycentric Parallel Aging Hypothesis, which evolved into PAF. I prepared the publication describing the model together with Mariusz Niemczyk.
As stated in the author contributions, I developed the conceptual framework, reviewed the literature and drafted the manuscript. Mariusz Niemczyk proposed the review, contributed to manuscript planning and provided academic supervision and manuscript revision.
Main publication on aging
Bartoszewicz M, Niemczyk M. The polycentric aging framework: epigenetic regulation as a dominant lifespan-limiting center in human aging. Aging. 2026;18:1365–1423. Published 9 October 2026. DOI: 10.18632/aging.206426.
Explore PAF Read the full publication
Reading this website
The Knowledge section guides readers through aging research. I consider study models, comparison groups, limitations and the functional significance of results. This website provides educational information.